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Thursday, 22 August 2019
Home » News items » Cervical Cancer is More Aggressive in Absence of Human Papilloma Virus

Cervical Cancer is More Aggressive in Absence of Human Papilloma Virus

Barcelona, 17 de April 2019
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Cytological specimen showing cervical cancer specifically squamous cell carcinoma in the cervix. Tissue is stained with pap stain and magnified x200 ©National Cancer Institute
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Cytological specimen showing cervical cancer specifically squamous cell carcinoma in the cervix. Tissue is stained with pap stain and magnified x200 ©National Cancer Institute

Cervical cancer negative for the human papilloma virus (HPV) is rare but more aggressive: it is more frequently diagnosed at advanced stages, with more metastasis and reduced survival. These are the conclusions of a study co-led by ISGlobal, an institution supported by ”la Caixa”, the Hospital Clinic and the University of Barcelona.  


In this study, the team led by ISGlobal researcher and pathologist Jaume Ordi, analysed tumours from 214 women diagnosed with cervical cancer and admitted to the Hospital Clinic in Barcelona between 2012 and 2015.


The new study confirms that HPV-negative tumours represent a more aggressive type of cancer with worse prognosis, which must be considered for the clinical management of these patients.

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